hrp0082p2-d1-536 | Puberty and Neuroendocrinology | ESPE2014

Monitoring GnRH Analog Treatment in Girls with Central Precocious Puberty: a Comparison of Four Methods

Zung Amnon , Burundukov Ella , Ulman Mira , Glaser Tamar , Chen Malka , Zadik Zvi

Background: The gold standard for adequate hormonal suppression during GnRHa treatment for precocious puberty (PP) is attenuated serum LH levels in response to LHRH stimulation.Objective and hypotheses: We aimed to compare basal and post-GnRHa levels of LH to LHRH stimulation test, and to evaluate first-voided urinary LH (ULH) as a non-invasive alternative method for monitoring treatment.Method: Seventeen girls with PP were followe...